Three-Dimensional Hepatocellular Carcinoma/Fibroblast Model on a Nanofibrous Membrane Mimics Tumor Cell Phenotypic Changes and Anticancer Drug Resistance

Three-dimensional (3D) in vitro tissue or organ models can effectively mimic the complex microenvironment of many types of human tissues for medical applications. Unfortunately, development of 3D cancer models, which involve cancer/stromal cells in a 3D environment, has remained elusive due to the e...

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Bibliographic Details
Main Authors: Binh Duong Le, Donggu Kang, Seokhwan Yun, Young Hun Jeong, Jong-Young Kwak, Sik Yoon, Songwan Jin
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Nanomaterials
Subjects:
Online Access:http://www.mdpi.com/2079-4991/8/2/64