A new synthetic matrix metalloproteinase inhibitor reduces human mesenchymal stem cell adipogenesis.

Development of adipose tissue requires the differentiation of less specialized cells, such as human mesenchymal stem cells (hMSCs), into adipocytes. Since matrix metalloproteinases (MMPs) play critical roles in the cell differentiation process, we conducted investigations to determine if a novel mer...

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Bibliographic Details
Main Authors: Dale B Bosco, Mark D Roycik, Yonghao Jin, Martin A Schwartz, Ty J Lively, Diego A R Zorio, Qing-Xiang Amy Sang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5325569?pdf=render