Disruption of human plasma cell differentiation by an environmental polycyclic aromatic hydrocarbon: a mechanistic immunotoxicological study

<p>Abstract</p> <p>Background</p> <p>The AhR is a ligand-activated transcription factor that mediates immunosuppression induced by environmental PAH and HAH. Recently, a critical role for the AhR in development of T cells involved in autoimmunity (Th17 and Treg) has bee...

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Bibliographic Details
Main Authors: Allan Lenka L, Sherr David H
Format: Article
Language:English
Published: BMC 2010-03-01
Series:Environmental Health
Online Access:http://www.ehjournal.net/content/9/1/15