A Mycobacterium tuberculosis Dormancy Antigen Differentiates Latently Infected Bacillus Calmette–Guérin-vaccinated Individuals

A Mycobacterium tuberculosis Dormancy Antigen Differentiates Latently Infected Bacillus Calmette–Guérin-vaccinated Individuals

IFN-γ release assays (IGRAs) are better indicators of Mycobacterium tuberculosis infection than the tuberculin skin test (TST) in Bacillus Calmette–Guérin (BCG)-vaccinated populations. However, IGRAs do not discriminate active and latent infections (LTBI) and no gold standard for LTBI diagnosis is a...

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Bibliographic Details
Main Authors: Delfina Peña, Ana I. Rovetta, Rodrigo E. Hernández Del Pino, Nicolás O. Amiano, Virginia Pasquinelli, Joaquín M. Pellegrini, Nancy L. Tateosian, Agustín Rolandelli, Marisa Gutierrez, Rosa M. Musella, Domingo J. Palmero, María M. Gherardi, Juan Iovanna, H. Eduardo Chuluyan, Verónica E. García
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:EBioMedicine
Subjects:
Latent tuberculosis
Active tuberculosis
Diagnosis
IFN-gamma
Antigens
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415300268

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http://www.sciencedirect.com/science/article/pii/S2352396415300268

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