Multiple Sclerosis-Like Symptoms in Mice Are Driven by Latent γHerpesvirus-68 Infected B Cells

Multiple sclerosis (MS) is caused by a combination of genetic and environmental factors. It is believed that previous infection with Epstein Barr Virus (EBV) plays an important role in the development of MS. Previously, we developed a murine model where latent infection with gamma herpesvirus 68 (γH...

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Bibliographic Details
Main Authors: Ana Citlali Márquez, Iryna Shanina, Marc Steven Horwitz
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Immunology
Subjects:
EAE
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.584297/full