The Effect of BAFF Inhibition on Autoreactive B-Cell Selection in Murine Systemic Lupus Erythematosus
Abstract The goal of this study was to determine how B-cell-activating factor of the TNF family (BAFF) availability influences selection of the autoreactive B-cell repertoire in NZB/W and NZW/BXSB lupus-prone mice bearing the site-directed heavy-chain transgene 3H9 that encodes for anti-dsDNA and an...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2016-02-01
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Series: | Molecular Medicine |
Online Access: | http://link.springer.com/article/10.2119/molmed.2016.00022 |