Nucleotide Excision Repair Factor XPC Ameliorates Prognosis by Increasing the Susceptibility of Human Colorectal Cancer to Chemotherapy and Ionizing Radiation

Nucleotide Excision Repair Factor XPC Ameliorates Prognosis by Increasing the Susceptibility of Human Colorectal Cancer to Chemotherapy and Ionizing Radiation

Nucleotide excision repair (NER) is a DNA damage repair mechanism in mammals, but the relationship between NER and human colorectal cancer (HRC) progression has not been clarified yet. In this study, the expression of the NER genes XPA, XPC, XPF, XPG, ERCC1, and XPD was measured in normal and cancer...

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Bibliographic Details
Main Authors: Liang-Bo Hu, Yin Chen, Xiao-Dong Meng, Pan Yu, Xu He, Jie Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Oncology
Subjects:
chemotherapy
colorectal neoplasms
nucleotide excision repair (NER)
prognosis
XPC
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00290/full

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https://www.frontiersin.org/article/10.3389/fonc.2018.00290/full

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