The Airways’ Mechanical Stress in Lung Disease: Implications for COPD Pathophysiology and Treatment Evaluation

The airway epithelium stretches and relaxes during the normal respiratory cycle, and hyperventilation exaggerates this effect, resulting in changes in lung physiology. In fact, stretching of the airways influences lung function and the secretion of airway mediators, which in turn may cause a potenti...

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Bibliographic Details
Main Authors: Pierachille Santus, Matteo Pecchiari, Francesco Tursi, Vincenzo Valenti, Marina Saad, Dejan Radovanovic
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2019/3546056