Myosin IXa binds AMPAR and regulates synaptic structure, LTP and cognitive function

Myosin IXa binds AMPAR and regulates synaptic structure, LTP and cognitive function

Myosin IXa (Myo9a) is a motor protein that is highly expressed in the brain. However, the role of Myo9a in neurons remains unknown. Here, we investigated Myo9a function in hippocampal synapses. In rat hippocampal neurons, Myo9a localizes to the postsynaptic density (PSD) and binds the alpha-amino-3-...

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Bibliographic Details
Main Authors: Alessandra eFolci, Luca eMurru, Elena eVezzoli, Luisa ePonzoni, Laura eGerosa, Edoardo eMoretto, Fabiana eLongo, Jonathan eZapata, Daniela eBraida, Francesco ePistillo, Martin eBähler, Maura eFrancolini, Mariaelvina eSala, Silvia eBassani
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
LTP
AMPAR
PSD
Myosin IXa
hippocampal synapses
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00001/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00001/full

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