Responses of Transgenic Melatonin-Enriched Goats on LPS Stimulation and the Proteogenomic Profiles of Their PBMCs

Responses of Transgenic Melatonin-Enriched Goats on LPS Stimulation and the Proteogenomic Profiles of Their PBMCs

The anti-inflammatory activity of melatonin (MT) has been well documented; however, little is known regarding endogenously occurring MT in this respect, especially for large animals. In the current study, we created a MT-enriched animal model (goats) overexpressing the MT synthetase gene Aanat. The...

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Bibliographic Details
Main Authors: Minghui Yang, Jingli Tao, Hao Wu, Lu Zhang, Yujun Yao, Lixi Liu, Tianqi Zhu, Hao Fan, Xudai Cui, Haoran Dou, Guoshi Liu
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
melatonin
proteogenomic analysis
LPS
PBMCs
inflammation
goat
Online Access:http://www.mdpi.com/1422-0067/19/8/2406

Internet

http://www.mdpi.com/1422-0067/19/8/2406

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