Human Pluripotent Stem Cells with Distinct X Inactivation Status Show Molecular and Cellular Differences Controlled by the X-Linked ELK-1 Gene

Female human pluripotent stem cells show vast heterogeneity regarding the status of X chromosome inactivation. By comparing the gene expression profile of cells with two active X chromosomes (XaXa cells) to that of cells with only one active X chromosome (XaXi cells), a set of autosomal genes was s...

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Bibliographic Details
Main Authors: Tal Bruck, Ofra Yanuka, Nissim Benvenisty
Format: Article
Language:English
Published: Elsevier 2013-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713003185