Study of the IgG endoglycosidase EndoS in group A streptococcal phagocyte resistance and virulence

<p>Abstract</p> <p>Background</p> <p>The secreted enzyme EndoS, an endoglycosidase from <it>Streptococcus pyogenes</it>, hydrolyzes the <it>N</it>-linked glycan of the constant region of immunoglobulin G (IgG) heavy chain and renders the antibody...

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Bibliographic Details
Main Authors: Collin Mattias, Okumura Cheryl YM, Sjögren Jonathan, Nizet Victor, Hollands Andrew
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Microbiology
Online Access:http://www.biomedcentral.com/1471-2180/11/120