Loss of Forkhead Box O3 Facilitates Inflammatory Colon Cancer: Transcriptome Profiling of the Immune Landscape and Novel TargetsSummary

Loss of Forkhead Box O3 Facilitates Inflammatory Colon Cancer: Transcriptome Profiling of the Immune Landscape and Novel TargetsSummary

Background & Aims: Diminished forkhead box O3 (FOXO3) function drives inflammation and cancer growth; however, mechanisms fostering these pathobiologies are unclear. Here, we aimed to identify in colon loss of FOXO3-dependent cellular and molecular changes that facilitate inflammation-mediated t...

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Bibliographic Details
Main Authors: Harrison M. Penrose, Chloe Cable, Sandra Heller, Nathan Ungerleider, Hani Nakhoul, Melody Baddoo, Alifiani B. Hartono, Sean B. Lee, Matthew E. Burow, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X18301486

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http://www.sciencedirect.com/science/article/pii/S2352345X18301486

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