SAAP-148 Eradicates MRSA Persisters Within Mature Biofilm Models Simulating Prosthetic Joint Infection

Prosthetic joint infection (PJI) is a severe complication of arthroplasty. Due to biofilm and persister formation current treatment strategies often fail. Therefore, innovative anti-biofilm and anti-persister agents are urgently needed. Antimicrobial peptides with their broad antibacterial activitie...

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Bibliographic Details
Main Authors: Henk Scheper, Julia M. Wubbolts, Joanne A. M. Verhagen, Adriëtte W. de Visser, Robert J. P. van der Wal, Leo G. Visser, Mark G. J. de Boer, Peter H. Nibbering
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.625952/full