Activator control of nucleosome occupancy in activation and repression of transcription.

The relationship between chromatin structure and gene expression is a subject of intense study. The universal transcriptional activator Gal4 removes promoter nucleosomes as it triggers transcription, but how it does so has remained obscure. The reverse process, repression of transcription, has often...

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Bibliographic Details
Main Authors: Gene O Bryant, Vidya Prabhu, Monique Floer, Xin Wang, Dan Spagna, David Schreiber, Mark Ptashne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-12-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2605919?pdf=render