Label-free X-ray estimation of brain amyloid burden

Abstract Amyloid plaque deposits in the brain are indicative of Alzheimer’s and other diseases. Measurements of brain amyloid burden in small animals require laborious post-mortem histological analysis or resource-intensive, contrast-enhanced imaging techniques. We describe a label-free method based...

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Bibliographic Details
Main Authors: Eshan Dahal, Bahaa Ghammraoui, Meijun Ye, J. Carson Smith, Aldo Badano
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-77554-5