Glutamine versus ammonia utilization in the NAD synthetase family.

NAD is a ubiquitous and essential metabolic redox cofactor which also functions as a substrate in certain regulatory pathways. The last step of NAD synthesis is the ATP-dependent amidation of deamido-NAD by NAD synthetase (NADS). Members of the NADS family are present in nearly all species across th...

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Bibliographic Details
Main Authors: Jessica De Ingeniis, Marat D Kazanov, Konstantin Shatalin, Mikhail S Gelfand, Andrei L Osterman, Leonardo Sorci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3376133?pdf=render