Assembly rules for GABAA receptor complexes in the brain

GABAA receptor (GABAAR) pentamers are assembled from a pool of 19 subunits, and variety in subunit combinations diversifies GABAAR functions to tune brain activity. Pentamers with distinct subunit compositions localize differentially at synaptic and non-synaptic sites to mediate phasic and tonic inh...

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Bibliographic Details
Main Authors: James S Martenson, Tokiwa Yamasaki, Nashid H Chaudhury, David Albrecht, Susumu Tomita
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/27443