Intranasal immunization with recombinant HA and mast cell activator C48/80 elicits protective immunity against 2009 pandemic H1N1 influenza in mice.

Pandemic influenza represents a major threat to global health. Vaccination is the most economic and effective strategy to control influenza pandemic. Conventional vaccine approach, despite being effective, has a number of major deficiencies including limited range of protection, total dependence on...

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Bibliographic Details
Main Authors: Shu Meng, Zhonghua Liu, Lili Xu, Li Li, Shan Mei, Linlin Bao, Wei Deng, Lina Li, Rongyue Lei, Liangzhi Xie, Chuan Qin, Linqi Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3098841?pdf=render