Essential role of GTP in epinephrine stimulation of human fat cell adenylate cyclase

Essential role of GTP in epinephrine stimulation of human fat cell adenylate cyclase

The activity of epinephrine-sensitive adenylate cyclase of human fat cell ghosts is markedly enhanced by the GTP analog 5'-guanylyl-imidodiphosphate (GMP-P(NH)P), but a similar effect of GTP itself has not been heretofore demonstrable. In the present work, comparison of adenylate cyclase activi...

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Bibliographic Details
Main Authors: M S Katz, J S Partilla, M A Piñeyro, R I Gregerman
Format: Article
Language:English
Published: Elsevier 1981-01-01
Series:Journal of Lipid Research
Subjects:
fat cells
guanine nucleotides
epinephrine
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520347465

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http://www.sciencedirect.com/science/article/pii/S0022227520347465

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