Germline-competent mouse-induced pluripotent stem cell lines generated on human fibroblasts without exogenous leukemia inhibitory factor.

Induced pluripotent stem (iPS) cells have attracted enormous attention due to their vast potential in regenerative medicine, pharmaceutical screening and basic research. Most prior established iPS cell lines were derived and maintained on mouse embryonic fibroblast (MEF) cells supplemented with exog...

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Bibliographic Details
Main Authors: Chunliang Li, Hongyao Yu, Yu Ma, Guilai Shi, Jing Jiang, Junjie Gu, Ying Yang, Shibo Jin, Zhe Wei, Hua Jiang, Jinsong Li, Ying Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2725300?pdf=render