Molecular Dissection of Cyclosporin A’s Neuroprotective Effect Reveals Potential Therapeutics for Ischemic Brain Injury

After the onset of brain ischemia, a series of events leads ultimately to the death of neurons. Many molecules can be pharmacologically targeted to protect neurons during these events, which include glutamate release, glutamate receptor activation, excitotoxicity, Ca2+ influx into cells, mitochondri...

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Bibliographic Details
Main Author: Minoru Kawakami
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:Brain Sciences
Subjects:
Online Access:http://www.mdpi.com/2076-3425/3/3/1325