Interplay between lipoproteins and bee venom phospholipase A2 in relation to their anti-plasmodium toxicity

We previously showed that the in vitro intraerythrocytic development of the malarial agent Plasmodium falciparum is strongly inhibited by secreted phospholipases A2 (sPLA2s) from animal venoms. Inhibition is dependent on enzymatic activity and requires the presence of serum lipoproteins in the paras...

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Bibliographic Details
Main Authors: Carole Guillaume, Catherine Calzada, Michel Lagarde, Joseph Schreével, Christiane Deregnaucourt
Format: Article
Language:English
Published: Elsevier 2006-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752033193X