Radiolabeled Anti-Claudin 4 and Anti-Prostate Stem Cell Antigen: Initial Imaging in Experimental Models of Pancreatic Cancer

Global expression profiling of pancreatic cancers has identified two cell surface molecules, claudin 4 and prostate stem cell antigen (PSCA), as being overexpressed in the vast majority of cases. Two antibodies, anti-claudin 4 and anti-PSCA, were radiolabeled with iodine 125 ( 125 I) for imaging pan...

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Bibliographic Details
Main Authors: Catherine A. Foss, James J. Fox, Georg Feldmann, Anirban Maitra, Christine Iacobuzio-Donohue, Scott E. Kern, Ralph Hruban, Martin G. Pomper
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2007-03-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2007.00010