Phosphodiesterase 3B is localized in caveolae and smooth ER in mouse hepatocytes and is important in the regulation of glucose and lipid metabolism.

Cyclic nucleotide phosphodiesterases (PDEs) are important regulators of signal transduction processes mediated by cAMP and cGMP. One PDE family member, PDE3B, plays an important role in the regulation of a variety of metabolic processes such as lipolysis and insulin secretion. In this study, the cel...

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Bibliographic Details
Main Authors: Karin Berger, Rebecka Lindh, Nils Wierup, Emilia Zmuda-Trzebiatowska, Andreas Lindqvist, Vincent C Manganiello, Eva Degerman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2650791?pdf=render