In Vitro Inhibitory and Cytotoxic Activity of MFM 501, a Novel Codonopsinine Derivative, against Methicillin-Resistant Staphylococcus aureus Clinical Isolates

28 new pyrrolidine types of compounds as analogues for natural polyhydroxy alkaloids of codonopsinine were evaluated for their anti-MRSA activity using MIC and MBC value determination assay against a panel of S. aureus isolates. One pyrrolidine compound, MFM 501, exhibited good inhibitory activity w...

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Bibliographic Details
Main Authors: Saiful Azmi Johari, Mastura Mohtar, Sharifah Aminah Syed Mohammad, Rohana Sahdan, Zurina Shaameri, Ahmad Sazali Hamzah, Mohd Fazli Mohammat
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/823829