Phosphodiesterase type 4 inhibitor rolipram improves survival of spiral ganglion neurons in vitro.

Sensorineural deafness is caused by damage of hair cells followed by degeneration of the spiral ganglion neurons and can be moderated by cochlear implants. However, the benefit of the cochlear implant depends on the excitability of the spiral ganglion neurons. Therefore, current research focuses on...

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Bibliographic Details
Main Authors: Katharina Kranz, Athanasia Warnecke, Thomas Lenarz, Martin Durisin, Verena Scheper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3958480?pdf=render