Synthesis of Saccharumoside-B analogue with potential of antiproliferative and pro-apoptotic activities

Synthesis of Saccharumoside-B analogue with potential of antiproliferative and pro-apoptotic activities

Abstract A new series of phenolic glycoside esters, saccharumoside-B and its analogs (9b-9n, 10) have been synthesized by the Koenigs-Knorr reaction. Antiproliferative activities of the compounds (9b-9n, 10) were evaluated on various cancer cell lines including, MCF-7 breast, HL-60 leukemia, MIA PaC...

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Main Authors: Srinuvasarao Rayavarapu, Nagendra Sastry Yarla, Sunanda Kumari Kadiri, Anupam Bishayee, Siddaiah Vidavalur, Ramu Tadikonda, Mahaboob Basha, Vijaya Rao Pidugu, Kaladhar S. V. G. K. Dowluru, Dhananjaya Bhadrapura Lakappa, Mohammad A. Kamal, Ghulam Md Ashraf, Vadim V. Tarasov, Vladimir N. Chubarev, Sergey G. Klochkov, George E. Barreto, Sergey O. Bachurin, Gjumrakch Aliev
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05832-w

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https://doi.org/10.1038/s41598-017-05832-w

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