Optimality conditions for cell-fate heterogeneity that maximize the effects of growth factors in PC12 cells.
Recently, the heterogeneity that arises from stochastic fate decisions has been reported for several types of cancer-derived cell lines and several types of clonal cells grown under constant environmental conditions. However, the relation between this stochasticity and the responsiveness to extracel...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC3828137?pdf=render |