Utility of the Bacteriophage RB69 Polymerase gp43 as a Surrogate Enzyme for Herpesvirus Orthologs

Viral polymerases are important targets in drug discovery and development efforts. Most antiviral compounds that are currently approved for treatment of infection with members of the herpesviridae family were shown to inhibit the viral DNA polymerase. However, biochemical studies that shed light on...

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Bibliographic Details
Main Authors: Nicholas Bennett, Matthias Götte
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/5/1/54