The IL-6/STAT3 Signaling Pathway Is an Early Target of Manuka Honey-Induced Suppression of Human Breast Cancer Cells

The IL-6/STAT3 Signaling Pathway Is an Early Target of Manuka Honey-Induced Suppression of Human Breast Cancer Cells

There is renewed interest in the potential use of natural compounds in cancer therapy. Previously, we demonstrated the anti-tumor properties of manuka honey (MH) against several cancers. However, the underlying mechanism and molecular targets of this activity remain unknown. For this study, the earl...

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Bibliographic Details
Main Authors: Priyanka Aryappalli, Sarah S. Al-Qubaisi, Samir Attoub, Junu A. George, Kholoud Arafat, Khalil B. Ramadi, Yassir A. Mohamed, Mezoon M. Al-Dhaheri, Ashraf Al-Sbiei, Maria J. Fernandez-Cabezudo, Basel K. al-Ramadi
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Oncology
Subjects:
triple-negative breast cancer
manuka honey
STAT3
interleukin-6
apoptosis
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00167/full

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http://journal.frontiersin.org/article/10.3389/fonc.2017.00167/full

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