Global characterization of interferon regulatory factor (IRF) genes in vertebrates: Glimpse of the diversification in evolution

<p>Abstract</p> <p>Background</p> <p>Interferon regulatory factors (IRFs), which can be identified based on a unique helix-turn-helix DNA-binding domain (DBD) are a large family of transcription factors involved in host immune response, haemotopoietic differentiation an...

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Bibliographic Details
Main Authors: Xu Zhen, Qi Zhi T, Huang Bei, Nie Pin
Format: Article
Language:English
Published: BMC 2010-05-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/11/22