Osteocyte-derived insulin-like growth factor I is not essential for the bone repletion response in mice.

The present study sought to evaluate the functional role of osteocyte-derived IGF-I in the bone repletion process by determining whether deficient expression of Igf1 in osteocytes would impair the bone repletion response to one week of dietary calcium repletion after two weeks of dietary calcium dep...

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Bibliographic Details
Main Authors: Kin-Hing William Lau, David J Baylink, Matilda H-C Sheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4312049?pdf=render