Recent Advances in Molecular Pharmacology of the Histamine Systems: Regulation of Histamine H1 Receptor Signaling by Changing Its Expression Level

Abstract.: Histamine H1 receptor (H1R) signaling is regulated by changing its expression level. Two mechanisms are involved in this regulation. One is down-regulation through receptor desensitization. Receptor phosphorylation seemed crucial because stimulation of the mutant H1R lacking five putative...

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Bibliographic Details
Main Authors: Miyoshi Katsuhiro, Das Asish Kumar, Fujimoto Katsumi, Horio Shuhei, Fukui Hiroyuki
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319344676