Fractalkine regulation of microglial physiology and consequences on the brain and behaviour

Neural circuits are constantly monitored and supported by the surrounding microglial cells, using finely tuned mechanisms which include both direct contact and release of soluble factors. These bidirectional interactions are not only triggered by pathological conditions as a S.O.S. response to noxio...

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Bibliographic Details
Main Authors: Rosa Chiara Paolicelli, Kanchan eBisht, Marie-Eve eTremblay
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00129/full