Plasmodium vivax Reticulocyte Binding Proteins Are Key Targets of Naturally Acquired Immunity in Young Papua New Guinean Children.

Plasmodium vivax Reticulocyte Binding Proteins Are Key Targets of Naturally Acquired Immunity in Young Papua New Guinean Children.

Major gaps in our understanding of Plasmodium vivax biology and the acquisition of immunity to this parasite hinder vaccine development. P. vivax merozoites exclusively invade reticulocytes, making parasite proteins that mediate reticulocyte binding and/or invasion potential key vaccine or drug targ...

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Bibliographic Details
Main Authors: Camila T França, Wen-Qiang He, Jakub Gruszczyk, Nicholas T Y Lim, Enmoore Lin, Benson Kiniboro, Peter M Siba, Wai-Hong Tham, Ivo Mueller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5038947?pdf=render

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http://europepmc.org/articles/PMC5038947?pdf=render

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