Olesoxime (TRO19622): A Novel Mitochondrial-Targeted Neuroprotective Compound

Olesoxime (TRO19622): A Novel Mitochondrial-Targeted Neuroprotective Compound

Olesoxime (TRO19622) is a novel mitochondrial-targeted neuroprotective compound undergoing a pivotal clinical efficacy study in Amyotrophic Lateral Sclerosis (ALS) and also in development for Spinal Muscular Atrophy (SMA). It belongs to a new family of cholesterol-oximes identified for its survival-...

Full description

Bibliographic Details
Main Authors: Rebecca M. Pruss, Jean-Louis Abitbol, Thierry Bordet, Patrick Berna
Format: Article
Language:English
Published: MDPI AG 2010-01-01
Series:Pharmaceuticals
Subjects:
TRO19622
olesoxime
neuroprotection
mitochondrial permeability transition pore
motor neuron disease
amyotrophic lateral sclerosis
spinal muscular atrophies
Online Access:http://www.mdpi.com/1424-8247/3/2/345/

Internet

http://www.mdpi.com/1424-8247/3/2/345/

Similar Items