Parkinson’s disease-associated protein Parkin: an unusual player in cancer

Abstract The mutation of the Parkin gene is a cause of familial Parkinson’s disease. A growing body of evidence suggests that Parkin also functions as a tumor suppressor. Parkin is an ubiquitin E3 ligase, and plays important roles in a variety of cellular processes implicated in tumorigenesis, inclu...

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Bibliographic Details
Main Authors: Juan Liu, Cen Zhang, Wenwei Hu, Zhaohui Feng
Format: Article
Language:English
Published: Wiley 2018-06-01
Series:Cancer Communications
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40880-018-0314-z