Prevalence of glutathione S-transferase gene deletions and their effect on sickle cell patients

Prevalence of glutathione S-transferase gene deletions and their effect on sickle cell patients

BACKGROUND: Glutathione S-transferase gene deletions are known detoxification agents and cause oxidative damage. Due to the different pathophysiology of anemia in thalassemia and sickle cell disease, there are significant differences in the pathophysiology of iron overload and iron-related complicat...

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Bibliographic Details
Main Authors: Pandey Sanjay, Mishra Rahasya Mani, Pandey Sweta, Shah Vineet, Ahuja Rajesh Kumar, Saxena Renu
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Revista Brasileira de Hematologia e Hemoterapia
Subjects:
glutathione transferase
anemia
sickle cell
hemoglobinopathies
polymerase chain reaction
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842012000200010

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842012000200010

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