Synthesis and Improved Cross-Linking Properties of C5-Modified Furan Bearing PNAs

Over the past decades, peptide nucleic acid/DNA (PNA:DNA) duplex stability has been improved via backbone modification, often achieved via introducing an amino acid side chain at the α- or γ-position in the PNA sequence. It was previously shown that interstrand cross-linking can further enhance the...

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Bibliographic Details
Main Authors: Joke Elskens, Alex Manicardi, Valentina Costi, Annemieke Madder, Roberto Corradini
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Molecules
Subjects:
PNA
Online Access:https://www.mdpi.com/1420-3049/22/11/2010