Dimeric bisbenzimidazoles DB(n) in combination with ionizing radiation decrease number and clonogenic activity of MCF-7 breast cancer stem cells
Purpose of the study was search for agents to eliminate the pool of cancer stem cells (CSCs) and increase their radiosensitivity among DNA minor groove binding ligands, synthetic dimeric bisbenzimidazoles of the DB(n) series, where n is the number of methylene groups in the linker connecting two bi...
Main Authors: | Irina A. Zamulaeva, Kristina A. Churyukina, Olga N. Matchuk, Alexander A. Ivanov, Vyacheslav O. Saburov, Alexei L. Zhuze |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2020-12-01
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Series: | AIMS Biophysics |
Subjects: | |
Online Access: | http://www.aimspress.com/article/doi/10.3934/biophy.2020024?viewType=HTML |
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