Progress towards non-small-cell lung cancer models that represent clinical evolutionary trajectories

Non-small-cell lung cancer (NSCLC) is the leading cause of cancer-related deaths worldwide. Although advances are being made towards earlier detection and the development of impactful targeted therapies and immunotherapies, the 5-year survival of patients with advanced disease is still below 20%. Ef...

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Bibliographic Details
Main Authors: Robert E. Hynds, Kristopher K. Frese, David R. Pearce, Eva Grönroos, Caroline Dive, Charles Swanton
Format: Article
Language:English
Published: The Royal Society 2021-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.200247