Dentate Gyrus Peroxiredoxin 6 Levels Discriminate Aged Unimpaired From Impaired Rats in a Spatial Memory Task

Dentate Gyrus Peroxiredoxin 6 Levels Discriminate Aged Unimpaired From Impaired Rats in a Spatial Memory Task

Similar to humans, the normal aged rat population is not homogeneous in terms of cognitive function. Two distinct subpopulations of aged Sprague–Dawley rats can be identified on the basis of spatial memory performance in the hole-board paradigm. It was the aim of the study to reveal protein changes...

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Bibliographic Details
Main Authors: Jana Lubec, Roman Smidak, Jovana Malikovic, Daniel Daba Feyissa, Volker Korz, Harald Höger, Gert Lubec
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
peroxiredoxin
PRDX6
aging
hole-board
proteomics
spatial memory
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00198/full

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https://www.frontiersin.org/article/10.3389/fnagi.2019.00198/full

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