Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties

Abstract Background Autoreactive Th1 and Th17 cells are believed to mediate the pathology of multiple sclerosis in the central nervous system (CNS). Their interaction with microglia and astrocytes in the CNS is crucial for the regulation of the neuroinflammation. Previously, we have shown that only...

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Bibliographic Details
Main Authors: Chittappen K. Prajeeth, Julius Kronisch, Reza Khorooshi, Benjamin Knier, Henrik Toft-Hansen, Viktoria Gudi, Stefan Floess, Jochen Huehn, Trevor Owens, Thomas Korn, Martin Stangel
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Journal of Neuroinflammation
Subjects:
Th1
Online Access:http://link.springer.com/article/10.1186/s12974-017-0978-3