Role of endoplasmic reticulum stress in alpha-TEA mediated TRAIL/DR5 death receptor dependent apoptosis.

Alpha-TEA (RRR-alpha-tocopherol ether-linked acetic acid analog), a derivative of RRR-alpha-tocopherol (vitamin E) exhibits anticancer actions in vitro and in vivo in variety of cancer types. The objective of this study was to obtain additional insights into the mechanisms involved in alpha-TEA indu...

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Bibliographic Details
Main Authors: Richa Tiwary, Weiping Yu, Jing Li, Sook-Kyung Park, Bob G Sanders, Kimberly Kline
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2912340?pdf=render