SIRT1-induced deacetylation of Akt expedites platelet phagocytosis and delays HEMEC aging

Maintaining the health of the endothelium is of critical importance to prevention against cell aging. The current study was performed to clarify the role of sirtuin1 (SIRT1) in platelet phagocytosis in cell aging and identified its downstream molecular mechanism. Platelet phagocytosis by human endom...

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Bibliographic Details
Main Authors: Yong Lan, Min Dong, Yongjun Li, Yongpeng Diao, Zuoguang Chen, Yangfang Li
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Akt
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121000238