The Fatty Acid β-Oxidation Pathway is Activated by Leucine Deprivation in HepG2 Cells: A Comparative Proteomics Study

Abstract Leucine (Leu) is a multifunctional essential amino acid that plays crucial role in various cellular processes. However, the integral effect of Leu on the hepatic proteome remains largely unknown. Here, we for the first time applied an isobaric tags for relative and absolute quantification (...

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Bibliographic Details
Main Authors: Guokai Yan, Xiuzhi Li, Ying Peng, Baisheng Long, Qiwen Fan, Zhichang Wang, Min Shi, Chunlin Xie, Li Zhao, Xianghua Yan
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02131-2