Physicochemical characterisation of dihydro-alpha-lipoic acid interaction with human serum albumin by multi-spectroscopic and molecular modelling approaches

The binding of a popular food supplement and well-known antioxidant, dihydro-alpha-lipoic acid (DHLA) to human serum albumin (HSA) was characterised. The binding was monitored by several spectroscopic methods together with the molecular docking approach. HSA was able to bind DHLA with moderate affin...

Full description

Bibliographic Details
Main Authors: Gligorijević Nikola, Šukalović Vladimir, Minić Simeon, Miljuš Goran, Nedić Olgica, Penezić Ana
Format: Article
Language:English
Published: Serbian Chemical Society 2021-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2021/0352-51392100041G.pdf