Differential cytokine profiles upon comparing selective versus classic glucocorticoid receptor modulation in human peripheral blood mononuclear cells and inferior turbinate tissue.

BACKGROUND:Glucocorticoid Receptor agonists, particularly classic glucocorticoids, are the mainstay among treatment protocols for various chronic inflammatory disorders, including nasal disease. To steer away from steroid-induced side effects, novel GR modulators exhibiting a more favorable therapeu...

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Bibliographic Details
Main Authors: Ilse M Beck, Koen Van Crombruggen, Gabriele Holtappels, François Daubeuf, Nelly Frossard, Claus Bachert, Karolien De Bosscher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395417?pdf=render