Neuronostatin Attenuates Myocardial Contractile Function through Inhibition of Sarcoplasmic Reticulum Ca2+-ATPase in Murine Heart

Neuronostatin Attenuates Myocardial Contractile Function through Inhibition of Sarcoplasmic Reticulum Ca2+-ATPase in Murine Heart

Background/Aims: Neuronostatin, derived from the somatostatin preprohormone, was recently identified to be produced by several tissues exerting a role in cardiovascular regulation and metabolism. Nonetheless, the precise mechanism behind neuronostatin-elicited myocardial responses remains elusive. M...

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Bibliographic Details
Main Authors: Xiaoling Zhu, Nan Hu, Xiyao Chen, Miao-Zhang Zhu, Hailong Dong, Xihui Xu, Fuling Luo, Yinan Hua, Sreejayan Nair, Willis K. Samson, Lize Xiong, Jun Ren
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Neuronostatin
Cardiac
Contractile
SERCA
AMPK
Online Access:http://www.karger.com/Article/FullText/362969

Internet

http://www.karger.com/Article/FullText/362969

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